Guides for RUO store owners
Choose the question in front of you: starting a brand, payments, website requirements or enforcement history.
General information for store operators, not legal advice. Read each article's sources and review date.
Starting a peptide brand
How to Start a Peptide Company in 2026: Operator's Guide
Plan the business model, sourcing, website, payments and professional advice your launch needs.
Choosing a Peptide Website Builder
What to look for in catalog guardrails, copy checks, checkout, admin tools and ongoing support.
Selling Peptides on Shopify: Platform Questions
Platform policies, payment-provider restrictions and alternatives to evaluate.
White Label Peptides: Planning Beyond the Supplier
The storefront, copy, payments and fulfillment work to plan alongside sourcing.
How Much It Costs to Start a Peptide Business (Real Math)
Build a budget for your website, stock, processing, reserves, testing and legal advice.
Peptide Dropshipping: How It Works and What It Costs
Compare inventory models and account for the costs between gross margin and net profit.
Marketing a Peptide Business: Channel Planning
Channel restrictions and planning for search, organic content, email and affiliates.
Do You Need a License to Sell Peptides? Direct Answer
Questions about business models, licensing and state requirements to discuss with counsel.
Payment problems & provider choices
Stripe Shut Down Your Peptide Store: First 24 Hours
Understand the closure notice, review held funds and plan your next payment steps.
Shopify Banned Your Peptide Store? Salvage + Next Steps
What to save from your store, which questions to ask and how to plan a migration.
Square Closed Your Peptide Account: What Happens Now
Read the deactivation notice, review the fund-release terms and evaluate replacement payment options.
PayPal Permanently Limited Your Peptide Business - Now What
Account limitations, held funds and the risks of trying to use another account.
Peptide Merchant Accounts: Preparing an Application
Website review, application preparation, processing rates and reserve requirements.
Best Payment Processor for Peptides: Independent Matrix
Compare card processing, ACH, crypto and P2P options, including fees, reserves and provider restrictions.
Peptide Payment Processing: Why It's Hard, What Works
Card-network monitoring, provider requirements and planning multiple payment options.
MATCH List and Peptides: Are You Blacklisted, and Now What
What a MATCH listing means, how to investigate it and what to discuss with prospective providers.
Why Did Peptide Sciences Shut Down? What We Actually Know
The documented record of the closure, questions left unanswered and warnings about impersonator sites.
Why Peptide Companies Are Shutting Down in 2026
Documented enforcement actions, payment terminations and platform restrictions affecting the category.
Zelle, Venmo and Cash App: Limits to Understand
Provider policies, operational limits and questions to review before relying on a P2P payment app.
Website requirements & legal questions
Selling Peptides Online: Questions for Your Counsel
Research-use positioning, product status and the legal questions a store owner needs to resolve.
FDA Warning Letters to Peptide Companies: 2024-2026 Tracker
A collection of warning letters and the website content discussed in each.
RUO Disclaimers: Wording and Limitations
What a disclaimer communicates and why surrounding website content matters.
FDA Intended Use Doctrine: How Peptide Sites Get Flagged
How intended-use analysis relates to website copy, imagery and related communications.
Peptide Website Review Checklist
A review of product restrictions, written claims, eligibility gates and consent records, with sources.
Is BPC-157 Legal to Sell in 2026? Status After the FDA Move
A sourced discussion of BPC-157 and TB-500 status and the questions left for a store's counsel.
FDA warning letter breakdowns
Gram Peptides FDA Warning Letter: Breakdown + Lessons
The products, copy and injection-kit references discussed in the letter.
Prime Sciences FDA Letter: Coded Peptide Names Don't Work
How the letter addressed coded product names and the compounds behind them.
PekCura Labs FDA Warning Letter: The Pattern Repeats
The letter's findings on coded compound names, with source references.
Summit Research Peptides: Intended Use and Disclaimers
How the letter discussed the website's content alongside its research-use disclaimer.
Pinnacle Peptides FDA Warning Letter: SARMs, Not GLP-1s
The SARMs and research-use marketing discussed in the letter.
Trackers & research
The Stonegate Compliance Index
Our storefront site-scan research, with results, observed issues and the scoring methodology.
2026 Peptide Enforcement Tracker
Documented FDA letters, seizures, sentencings and platform actions, with linked sources.
The RUO Operator (weekly brief)
A weekly brief on enforcement developments, payment providers and store operations.
Apply the reading to your store.
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